Paediatric clinical Research Infrastructure Service Model
A coordinated, transnational ecosystem supporting paediatric clinical research across Europe and Canada.
Children make up 14% of Europe's population, yet remain significantly under-represented in clinical research — a gap that highlights the need for a coordinated, transnational ecosystem of infrastructures and service organisations.
PRISM brings together 23 organisations from Europe and Canada to change this, offering end-to-end support — from study design to execution — for multinational paediatric clinical trials.
PRISM at a glance
One consortium, two continents
Coordinated by ECRIN, PRISM unites 23 partners: clinical research infrastructures, hospital networks, universities, digital health SMEs, patient organisations and school associations from Europe and Canada.
Three access routes
Full operational support for selected trials (TNA1 — Transnational Access for study execution), upstream methodological consulting (TNA2), and virtual access to digital and AI-powered tools (VA1).
A lasting infrastructure
Beyond the project's lifetime, PRISM will establish a digital marketplace and a joint access mechanism, sustaining support for paediatric clinical research in Europe and Canada long after the funding period ends.
News
Thank you for joining the PRISM TNA1 Call webinar
More than 140 researchers, clinicians, networks and research support teams joined us. Watch the replay and find the full call text and application platform.
PRISM first Open Call (TNA1) for paediatric clinical studies
Academic and non-commercial sponsors can submit a Letter of Intent until 31 December 2026, 17:00 CET, for access to coordinated, end-to-end trial management services for multinational paediatric studies in Europe and Canada.
PRISM consortium holds its official kick-off meeting
All 23 PRISM partner organisations from across Europe and Canada met in Paris on 7 and 8 September 2026 for the project's official kick-off meeting, hosted by coordinator ECRIN.
Planning to run a multinational paediatric clinical research project?
PRISM's first call for proposals is now open. Letters of Intent are due by 31 December 2026.
Open calls